The ADNP Polyclonal Antibody (CAB4546) is a valuable tool for researchers studying the activity of activity-dependent neuroprotector homeobox (ADNP), a protein involved in brain development and cognitive function. This antibody, generated in rabbits, is highly specific to ADNP and has been validated for use in various experimental techniques, including Western blot and immunofluorescence.ADNP is a critical player in neuronal development and function, with implications in neurodegenerative disorders such as Alzheimer's disease.
By targeting ADNP with this antibody, researchers can gain insights into its role in these diseases and potentially identify new therapeutic targets. Additionally, the ADNP Polyclonal Antibody is suitable for use in a wide range of sample types, making it a versatile tool for neuroscience research.
Product Name:
ADNP Rabbit Polyclonal Antibody
SKU:
CAB4546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 843-1102 of human ADNP (NP_056154.1).
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Purification Method:
Affinity purification
Gene ID:
23394
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADNP Antibody (CAB4546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
