The ADK Polyclonal Antibody (CAB15024) is a valuable tool for researchers studying adenosine kinase (ADK), an enzyme involved in the regulation of extracellular adenosine levels. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for Western blot applications. By binding specifically to ADK protein, this antibody enables the accurate detection and analysis of ADK in various cell types.ADK plays a crucial role in the metabolism of adenosine, a key signaling molecule involved in processes such as energy metabolism, neurotransmission, and immune regulation. Dysregulation of ADK activity has been implicated in conditions such as epilepsy, stroke, and cancer, making it an attractive target for therapeutic intervention.
By studying ADK using this antibody, researchers can gain valuable insights into the role of adenosine signaling in various physiological and pathological processes.Overall, the ADK Polyclonal Antibody (CAB15024) is a versatile tool that can assist researchers in uncovering the molecular mechanisms underlying adenosine metabolism and its impact on health and disease. Its high specificity and sensitivity make it an essential component in studies focusing on ADK and its potential therapeutic implications.
Product Name:
ADK Rabbit Polyclonal Antibody
SKU:
CAB15024
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-345 of human ADK (NP_001114.2).
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADK Rabbit pAb (CAB15024) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
