The ADK Polyclonal Antibody (CAB15023) is a valuable tool for researchers studying adenosine kinase (ADK), an enzyme involved in the regulation of adenosine levels in the body. ADK is known to play an important role in purine metabolism and is implicated in various biological processes, including inflammation, immune response, and neurotransmission.This antibody, produced in rabbits, is highly specific to human ADK and has been validated for use in Western blot applications. Its binding affinity to ADK allows for accurate detection and quantification of the enzyme in different experimental settings, making it an essential tool for studies in biochemistry, pharmacology, and neuroscience.The ADK Polyclonal Antibody is particularly useful for investigating the role of ADK in various diseases, such as cancer, neurodegenerative disorders, and autoimmune conditions.
By understanding the regulation and activity of ADK, researchers can gain insights into the molecular mechanisms underlying these diseases and identify potential therapeutic targets for intervention.Overall, the ADK Polyclonal Antibody is a reliable and effective reagent for research aimed at unraveling the functions of ADK and its implications in health and disease. Its high specificity and sensitivity make it a valuable asset for scientists seeking to advance our knowledge of adenosine metabolism and its impact on human physiology.
Product Name:
ADK Rabbit Polyclonal Antibody
SKU:
CAB15023
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-345 of human ADK (NP_001114.2).
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADK Rabbit pAb (CAB15023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
