The Adipor2 Polyclonal Antibody (CAB12777) is a crucial tool for researchers studying Adipor2, a cell surface receptor involved in regulating metabolic processes and energy homeostasis. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Adipor2 plays a key role in adiponectin signaling, which influences glucose and lipid metabolism, making it a significant target for research in obesity, diabetes, and metabolic diseases. By binding specifically to the Adipor2 protein, this antibody allows for the detection and analysis of Adipor2 expression in various cell types, making it an essential component for studies in metabolic disorders and related fields.
Understanding the functions and mechanisms of Adipor2 is essential for uncovering its potential implications in disease and developing potential therapeutic interventions. The Adipor2 Polyclonal Antibody provides researchers with a reliable tool to explore the role of Adipor2 in metabolic regulation and its potential as a target for therapeutic strategies.
Product Name:
ADIPOR2 Rabbit Polyclonal Antibody
SKU:
CAB12777
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human ADIPOR2 (NP_078827.2).
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).
Purification Method:
Affinity purification
Gene ID:
79602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using ADIPOR2 Rabbit pAb (CAB12777) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
