The Adipor1 Polyclonal Antibody (CAB16527) is a vital tool for researchers studying adipor1, a key cell surface receptor involved in regulating metabolism and energy balance. This antibody, produced in rabbits, exhibits high specificity for adipor1 in human samples and has been validated for use in Western blot applications.Adipor1, also known as adiponectin receptor 1, plays a crucial role in mediating the metabolic effects of adiponectin, a hormone that regulates glucose levels and fatty acid breakdown. Dysregulation of adipor1 signaling has been linked to metabolic disorders such as obesity, insulin resistance, and type 2 diabetes, making it a promising target for therapeutic intervention.
By using the Adipor1 Polyclonal Antibody, researchers can accurately detect and analyze adipor1 protein expression in a variety of cell types, facilitating investigations into the molecular mechanisms underlying metabolic diseases. This antibody is a valuable resource for studies aimed at uncovering new therapeutic strategies for managing metabolic disorders and improving overall health.
Product Name:
ADIPOR1 Rabbit Polyclonal Antibody
SKU:
CAB16527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human Adiponectin Receptor 1 (NP_057083.2).
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADIPOR1 Rabbit pAb (CAB16527) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
