The Adipor1 Polyclonal Antibody (ABC00001) is a valuable tool for researchers studying Adipor1, a cell surface receptor that plays a key role in regulating energy metabolism and insulin sensitivity. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, allowing for precise detection and analysis of Adipor1 protein expression in various cell types.Adipor1, also known as adiponectin receptor 1, is a critical component in the regulation of adiponectin signaling pathways, which are involved in metabolic processes such as glucose metabolism and fatty acid oxidation.
Dysregulation of Adipor1 signaling has been implicated in metabolic disorders such as obesity and type 2 diabetes, making it a promising target for therapeutic intervention.By studying the function and expression of Adipor1 with the use of this polyclonal antibody, researchers can gain valuable insights into the molecular mechanisms underlying metabolic disorders and potentially discover new therapeutic strategies to combat these diseases. With its specificity and reliability, the Adipor1 Polyclonal Antibody is an essential tool for advancing research in the fields of metabolism, endocrinology, and obesity-related conditions.
Product Name:
ADIPOR1 Polyclonal Antibody
SKU:
CAB21533
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-136 of human ADIPOR1 (NP_057083.2).
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADIPOR1 Rabbit pAb (CAB21533) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
