ADIPOQ Antibody (PACO35938)
- SKU:
- PACO35938
- Product Type:
- Antibody
- Reactivity:
- Bovine
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADIPOQ Antibody (PACO35938) |
Antibody SKU: | PACO35938 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Bovine |
Immunogen: | Recombinant Bovine Adiponectin protein (18-240AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid, combustion. Antagonizes TNF-α by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW |
Synonyms: | Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1), ADIPOQ, ACRP30 APM1 |
UniProt Protein Function: | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW (). |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q3Y5Z3 |
NCBI GenInfo Identifier: | 27807433 |
NCBI Gene ID: | 282865 |
NCBI Accession: | NP_777167.1 |
UniProt Secondary Accession: | Q3Y5Z3,Q95MQ4, A5D7A8 |
UniProt Related Accession: | Q3Y5Z3 |
Molecular Weight: | 26,133 Da |
NCBI Full Name: | adiponectin |
NCBI Synonym Full Names: | adiponectin, C1Q and collagen domain containing |
NCBI Official Symbol: | ADIPOQÂ Â |
NCBI Official Synonym Symbols: | APM1; ACRP30Â Â |
NCBI Protein Information: | adiponectin |
UniProt Protein Name: | Adiponectin |
UniProt Synonym Protein Names: | 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1 |
Protein Family: | |
UniProt Gene Name: | ADIPOQÂ Â |
UniProt Entry Name: |