The AdipoQ Polyclonal Antibody (PACO35938) is a valuable tool for researchers studying AdipoQ, a protein involved in adipocyte differentiation and insulin sensitivity. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting and immunohistochemistry applications.AdipoQ, also known as adiponectin, is a key regulator of metabolic homeostasis and has been linked to various metabolic disorders, including obesity and type 2 diabetes. By targeting AdipoQ with this antibody, researchers can investigate its role in metabolic pathways and potentially identify therapeutic targets for metabolic diseases.
This antibody provides researchers with a powerful tool for studying the function of AdipoQ in both normal and pathological conditions, making it a valuable asset for studies in metabolic research and drug development. With its high specificity and sensitivity, the AdipoQ Polyclonal Antibody is essential for exploring the complex mechanisms underlying metabolic disorders and identifying novel therapeutic interventions.
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid, combustion. Antagonizes TNF-α by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW ().
