null

ADI1 Monoclonal Antibody [PAT27E8A] (CPAB0171)

SKU:
CPAB0171
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT27E8A
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

ADI1 Monoclonal Antibody [PAT27E8A] (CPAB0171)

The ADI1 Polyclonal Antibody (CPAB0171) is a valuable tool for researchers studying ADI1, a key enzyme involved in the biosynthesis of biotin, a vital cofactor in various metabolic processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the ADI1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in biochemistry and metabolic research.

ADI1, also known as acireductone dioxygenase 1, plays a crucial role in maintaining biotin levels within the cell, essential for processes such as fatty acid synthesis and amino acid metabolism. Dysregulation of ADI1 activity has been linked to biotin deficiencies and metabolic disorders, highlighting its importance in overall health and metabolism. Research into ADI1 function can provide insights into potential therapeutic strategies for treating biotin-related disorders and metabolic imbalances.

Product Name:ADI1 Antibody
Product Sku:CPAB0171
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ADI1 mAb, clone PAT27E8A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ADI1 protein 1-179 amino acids purified from Ecoli.
Clone:PAT27E8A.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:
Isotype:IgG1
Background:Acireductone dioxygenase 1 (ADI1) is a part of the acireductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. ADI1 regulates mRNA processing in the nucleus, and carries out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. ADI1 down-regulates cell migration arbitrated by MMP14.
Synonyms:APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, SIPL, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, Acireductone dioxygenase, Fe-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, Submergence-induced protein-like factor.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products