The ADHFE1 Antibody (PAC019075) is a polyclonal antibody specifically designed for research involving ADHFE1, an enzyme involved in glycolysis and fatty acid metabolism. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.ADHFE1, also known as alcohol dehydrogenase iron-containing protein 1, plays a crucial role in cellular metabolism, particularly in the breakdown and utilization of glucose and fatty acids. Dysregulation of ADHFE1 has been implicated in various metabolic disorders and diseases, making it an important target for research in the fields of metabolism, obesity, and diabetes.
The ADHFE1 Antibody enables the detection and analysis of ADHFE1 protein expression in different cell types and tissues, providing valuable insights into its role in metabolic pathways and disease development. By understanding the function of ADHFE1, researchers can potentially uncover new therapeutic targets and strategies for treating metabolic disorders and related conditions.
Antibody Name:
ADHFE1 Antibody (PACO19075)
Antibody SKU:
PACO19075
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human ADHFE1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19075(ADHFE1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19075(ADHFE1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The ADHFE1 gene encodes hydroxyacid, oxoacid, transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).
