The ADHFE1 Polyclonal Antibody (PAC019074) is a valuable tool for researchers studying the ADHFE1 protein, which is involved in multiple cellular processes, including lipid metabolism and oxidative stress response. This antibody, raised in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications.ADHFE1, a member of the alcohol dehydrogenase superfamily, plays a crucial role in maintaining cellular homeostasis by participating in the metabolism of aldehydes and ketones. Dysregulation of ADHFE1 has been linked to various diseases, including metabolic disorders and cancer, making it a promising target for therapeutic interventions.
The ADHFE1 Polyclonal Antibody enables precise detection and quantification of ADHFE1 protein levels in different cell types, providing valuable insights into its function and potential implications in disease pathogenesis. Its utility in research related to lipid metabolism, oxidative stress, and cancer biology makes it an invaluable tool for scientists investigating novel therapeutic strategies and molecular mechanisms underlying these conditions.
Antibody Name:
ADHFE1 Antibody (PACO19074)
Antibody SKU:
PACO19074
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human ADHFE1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO19074(ADHFE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19074(ADHFE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The ADHFE1 gene encodes hydroxyacid, oxoacid, transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).
