The ADH5 Polyclonal Antibody (CAB13459) is a valuable tool for research purposes in the field of biology, specifically in the study of the ADH5 protein. The antibody is produced in rabbits and has been shown to have high reactivity with human samples, making it ideal for use in Western blot applications. By binding to the ADH5 protein, this antibody allows for the detection and analysis of ADH5 in various cell types, making it a versatile option for researchers in immunology and cancer research.ADH5, also known as alcohol dehydrogenase 5, is an enzyme that plays a crucial role in the metabolism of alcohol and other toxic substances in the liver.
Studies have shown that ADH5 may also be involved in other physiological processes, making it a potentially important target for further research. Understanding the function and regulation of ADH5 could help shed light on various disease states, including liver disease and metabolic disorders.Overall, the ADH5 Polyclonal Antibody (CAB13459) offers researchers a reliable tool for investigating the role of ADH5 in health and disease. Its high reactivity and specificity make it a valuable asset for those studying the metabolism of alcohol, liver function, and related fields.
Product Name:
ADH5 Rabbit Polyclonal Antibody
SKU:
CAB13459
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADH5/GSNOR (NP_000662.3).
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Purification Method:
Affinity purification
Gene ID:
128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADH5/GSNOR antibody (CAB13459) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
