ADH5 Rabbit Polyclonal Antibody (CAB13459)
- SKU:
- CAB13459
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ADH5 Rabbit Polyclonal Antibody |
SKU: | CAB13459 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADH5/GSNOR (NP_000662.3). |
Sequence: | MANE VIKC KAAV AWEA GKPL SIEE IEVA PPKA HEVR IKII ATAV CHTD AYTL SGAD PEGC FPVI LGHE GAGI VESV GEGV TKLK AGDT VIPL YIPQ CGEC KFCL NPKT NLCQ KIRV TQGK GLMP DGTS RFTC KGKT ILHY MGTS TFSE YTVV ADIS VAKI DPLA PLDK VCLL GCGI STGY GAAV NTAK LEPG SVCA VFGL GGVG LAVI MGCK VAGA SRII GVDI NKDK FARA KEFG ATEC INPQ DFSK PIQE VLIE MTDG GVDY SFEC IGNV KVMR AALE ACHK GWGV SVVV GVAA SGEE IATR PFQL VTGR TWKG TAFG GWKS VESV PKLV SEYM SKKI KVDE FVTH NLSF DEIN KAFE LMHS GKSI RTVV KI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | FDH; ADHX; ADH-3; AMEDS; BMFS7; FALDH; GSNOR; GSH-FDH; HEL-S-60p; ADH5/GSNOR |
Positive Sample: | K-562,Mouse brain,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Purification Method: | Affinity purification |
Gene ID: | 128 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |