The ADH1B Polyclonal Antibody (CAB1431) is specifically designed for research involving the ADH1B protein, a key enzyme involved in alcohol metabolism. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the ADH1B protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in alcohol metabolism, liver function, and related research areas.ADH1B, a member of the alcohol dehydrogenase family, plays a crucial role in the breakdown of alcohol in the liver. Variations in the ADH1B gene have been linked to differences in alcohol metabolism and susceptibility to alcohol-related diseases.
Understanding the function and regulation of ADH1B is essential for investigating the effects of alcohol on the body and developing treatments for alcohol-related conditions.Researchers studying alcohol metabolism, liver diseases, and the impact of alcohol consumption on health will find the ADH1B Polyclonal Antibody (CAB1431) to be a valuable tool for their experiments. Its high specificity and sensitivity make it ideal for detecting ADH1B expression levels and studying the mechanisms underlying alcohol metabolism.
Product Name:
ADH1B Rabbit Polyclonal Antibody
SKU:
CAB1431
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-375 of human ADH1B (NP_000659.2).
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
125
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of rat liver, using ADH1B antibody (CAB1431) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
