The ADH1A/ADH1B/ADH1C Rabbit Polyclonal Antibody (CAB18581) is a valuable tool for researchers studying alcohol dehydrogenase enzymes, specifically isoforms ADH1A, ADH1B, and ADH1C. These enzymes play a crucial role in alcohol metabolism, converting alcohol into acetaldehyde in the liver. The antibody, raised in rabbits, is highly specific and reactive with human samples, making it a reliable choice for immunohistochemistry and Western blot applications.ADH1A, ADH1B, and ADH1C are key players in ethanol metabolism, with variations in these genes affecting an individual's alcohol tolerance and susceptibility to alcohol-related diseases.
By targeting these specific isoforms, researchers can gain insights into the mechanisms of alcohol metabolism and its implications in conditions such as alcohol dependence and liver diseases.Studying the expression and function of ADH1A, ADH1B, and ADH1C is essential for understanding alcohol metabolism and its impact on health. The ADH1A/ADH1B/ADH1C Rabbit Polyclonal Antibody (CAB18581) provides researchers with a reliable tool to investigate the roles of these enzymes in various research fields, including pharmacology, toxicology, and alcohol-related disorders.
Product Name:
ADH1A/ADH1B/ADH1C Rabbit Polyclonal Antibody
SKU:
CAB18581
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 270-370 of human ADH1A/ADH1B/ADH1C (NP_000659.2).
Alcohol dehydrogenase,consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
Purification Method:
Affinity purification
Gene ID:
124/125/126
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using ADH1A/ADH1B/ADH1C Rabbit pAb (CAB18581) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
