The ADGRE1 Polyclonal Antibody (CAB18637) is a valuable tool for researchers studying ADGRE1, a cell surface receptor involved in immune regulation and inflammation. Raised in rabbits, this antibody is highly specific for human samples and is validated for use in Western blot applications. By binding to the ADGRE1 protein, this antibody allows for precise detection and analysis in various cell types, making it well-suited for studies in immunology and cancer research.ADGRE1, also known as the adhesion G protein-coupled receptor E1, is known to play a crucial role in immune response modulation and cell adhesion processes.
Its involvement in regulating inflammatory responses makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By further understanding the function of ADGRE1, researchers may uncover potential therapeutic strategies to manipulate immune responses in these disease contexts.
Product Name:
F4/80 Rabbit Polyclonal Antibody
SKU:
CAB18637
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 367-645 of mouse F4/80 (NP_034260.1).
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and adaptive immune response. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system; and intestine. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1).
Purification Method:
Affinity purification
Gene ID:
13733
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using F4/80 Rabbit pAb (CAB18637) at 1:2000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 90s.
