The ADGRD1 Polyclonal Antibody (CAB12629) is a valuable tool for researchers studying ADGRD1, a G protein-coupled receptor implicated in various cellular processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for a range of applications including Western blot analysis. By binding to the ADGRD1 protein, this antibody allows for the detection and analysis of ADGRD1 expression in different cell types, making it ideal for studies in neuroscience and cell signaling research.
ADGRD1, also known as GPR133, is involved in diverse physiological functions such as neuronal development, cell migration, and signal transduction. Its dysregulation has been linked to neurological disorders and cancer, making it a promising target for therapeutic interventions. Investigating the role of ADGRD1 using this antibody can provide valuable insights into its molecular mechanisms and potential clinical applications in the fields of neurobiology and oncology.
Product Name:
ADGRD1 Rabbit Polyclonal Antibody
SKU:
CAB12629
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 805-874 of human ADGRD1 (NP_942122.2).
The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).
Purification Method:
Affinity purification
Gene ID:
283383
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADGRD1 Rabbit pAb (CAB12629) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
