The ADGRB3 Polyclonal Antibody (CAB11956) is specifically designed for research involving the ADGRB3 protein, also known as the G protein-coupled receptor B3. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. It targets the ADGRB3 protein, allowing for easy detection and analysis in a variety of cell types, making it an ideal tool for studies in neuroscience and drug development research.ADGRB3 is a cell surface receptor that plays a crucial role in mediating neurobiological processes such as synaptic plasticity, neuronal development, and synaptic transmission.
Its involvement in these pathways highlights its importance as a potential therapeutic target for neurological disorders such as Alzheimer's disease, schizophrenia, and autism spectrum disorders. Investigating the function of ADGRB3 is essential for uncovering potential treatment avenues for these conditions and advancing our understanding of brain function.
Product Name:
ADGRB3 Rabbit Polyclonal Antibody
SKU:
CAB11956
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1).
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis.
Purification Method:
Affinity purification
Gene ID:
577
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using ADGRB3 Rabbit pAb (CAB11956) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
