The ADCYAP1R1 Polyclonal Antibody (CAB3120) is a valuable tool for researchers studying the ADCYAP1R1 protein, which is involved in various cellular processes and signaling pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for use in Western blot applications.ADCYAP1R1, also known as PAC1 receptor, plays a crucial role in mediating the effects of pituitary adenylate cyclase-activating polypeptide (PACAP), a neuropeptide involved in the regulation of stress response, neurotransmission, and immune functions. The ADCYAP1R1 Polyclonal Antibody enables researchers to detect and analyze the expression of ADCYAP1R1 in different cell types, providing insights into its role in various physiological and pathological conditions.
Understanding the function and regulation of ADCYAP1R1 is essential for advancing research in neuroscience, endocrinology, and immunology, with potential implications for the development of novel therapeutics targeting the PACAP signaling pathway. The ADCYAP1R1 Polyclonal Antibody serves as a valuable tool for investigating the molecular mechanisms involving ADCYAP1R1 and its potential as a therapeutic target in a range of diseases and disorders.
Product Name:
ADCYAP1R1 Rabbit Polyclonal Antibody
SKU:
CAB3120
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-140 of human ADCYAP1R1 (NP_001109.2).
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
117
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart , using ADCYAP1R1 Rabbit pAb (CAB3120) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
