The ADCY3 Polyclonal Antibody (CAB7870) is a valuable tool for researchers studying ADCY3, a key enzyme involved in intracellular signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the ADCY3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in signal transduction and cellular communication.ADCY3, also known as adenylate cyclase 3, plays a crucial role in producing the second messenger molecule cAMP, which regulates various cellular processes such as gene expression, metabolism, and neurotransmission.
Dysregulation of ADCY3 has been linked to diseases including obesity, diabetes, and cardiovascular disorders, making it a promising therapeutic target for drug development and personalized medicine approaches.By using the ADCY3 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of ADCY3 in normal and diseased states, paving the way for potential new treatments and interventions in the field of metabolic and cardiovascular research.
Product Name:
ADCY3 Rabbit Polyclonal Antibody
SKU:
CAB7870
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human ADCY3 (NP_004027.2).
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
109
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADCY3 antibody (CAB7870) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.