The ADCY10 Polyclonal Antibody (CAB18473) is a valuable tool for researchers studying ADCY10, a key enzyme involved in the production of cyclic adenosine monophosphate (cAMP). This rabbit polyclonal antibody is highly specific and reacts with human samples, making it ideal for Western blot applications.ADCY10 plays a crucial role in various cellular processes, including cell proliferation, differentiation, and signal transduction. Dysregulation of ADCY10 has been implicated in several diseases, such as cancer, cardiovascular disorders, and neurological conditions.
By using this antibody, researchers can detect and analyze ADCY10 levels in different cell types, providing insights into its functions and potential therapeutic targeting.With its high reactivity, specificity, and validation for Western blotting, the ADCY10 Polyclonal Antibody (CAB18473) is a reliable tool for studies in molecular biology, pharmacology, and drug development. This antibody enables researchers to explore the role of ADCY10 in health and disease, paving the way for advancements in personalized medicine and targeted therapies.
Product Name:
ADCY10 Rabbit Polyclonal Antibody
SKU:
CAB18473
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human ADCY10 (NP_060887.2).
apical plasma membrane, cytoplasm, cytoskeleton, cytosol, dendrite, extracellular region, growth cone, mitochondrion, nucleus, perinuclear region of cytoplasm
Calculated MW:
187kDa
Observed MW:
48kDa
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
55811
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADCY10 Rabbit pAb (CAB18473) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
