The ADCK2 Polyclonal Antibody (PACO37070) is an essential tool for researchers studying the ADCK2 protein, a key player in mitochondrial function and energy metabolism. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the ADCK2 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cell biology, metabolism, and neurodegenerative diseases.
ADCK2, also known as a putative protein kinase, is involved in the regulation of mitochondrial biogenesis and function. Dysregulation of ADCK2 has been linked to various metabolic disorders and neurodegenerative conditions, highlighting its importance in maintaining cellular energy balance and overall health. Research into the functions of ADCK2 can provide valuable insights into the mechanisms underlying these diseases and potential therapeutic targets for intervention.
Western blot. All lanes: Adck2 antibody at 2µg/ml + K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/15000 dilution. Predicted band size: 69 kDa. Observed band size: 69 kDa.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37070 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO37070 at dilution of 1:100.
Background:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
Synonyms:
Uncharacterized aarF domain-containing protein kinase 2 (EC 2.7.11.-), Adck2
UniProt Protein Function:
ADCK2: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). Belongs to the protein kinase superfamily. ADCK protein kinase family.Protein type: EC 2.7.11.-; Membrane protein, integral; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical; EC 2.7.-.-; ATYPICAL group; ABC1 family; ABC1-C subfamilyCellular Component: mitochondrion
