The ADCK2 Polyclonal Antibody (PAC021885) is a valuable tool for researchers studying ADCK2, a protein involved in mitochondria-related processes such as oxidative phosphorylation and cellular energy production. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ADCK2, also known as AarF domain-containing protein kinase 2, is crucial for maintaining mitochondrial function and cell viability. Its role in energy metabolism and potential implications in diseases like mitochondrial disorders and neurodegenerative diseases make it a promising target for further investigation.
With the ADCK2 Polyclonal Antibody, researchers can effectively detect and study the expression of ADCK2 in various cell types, aiding in the understanding of its molecular function and its potential as a therapeutic target. This antibody is ideal for use in studies related to mitochondrial biology, energy metabolism, and neurological disorders.
Antibody Name:
ADCK2 Antibody (PACO21885)
Antibody SKU:
PACO21885
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ADCK2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen The MGC Project Team, Genome Res. 14:2121-2127(2004).
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells and K562 cells, using ADCK2 antibody.
Synonyms:
Uncharacterized aarF domain-containing protein kinase 2; EC 2.7.11; ADCK2; AARF;
UniProt Protein Function:
ADCK2: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). Belongs to the protein kinase superfamily. ADCK protein kinase family.
UniProt Protein Details:
Protein type:Kinase, protein; Protein kinase, atypical; Protein kinase, Ser/Thr (non-receptor); EC 2.7.-.-; EC 2.7.11.-; Membrane protein, integral; ATYPICAL group; ABC1 family; ABC1-C subfamily
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: mitochondrion; integral to membrane
Molecular Function:protein serine/threonine kinase activity; ATP binding
Biological Process: protein amino acid phosphorylation
