The ADCK1 Polyclonal Antibody (PAC015319) is a valuable tool for research involving ADCK1, a mitochondrial protein that plays a role in the biosynthesis of coenzyme Q (CoQ). This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the ADCK1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in mitochondrial biology and bioenergetics research.
ADCK1 is a key player in the biosynthetic pathway of CoQ, an essential component of the electron transport chain in mitochondria. Dysfunction of the CoQ biosynthesis pathway has been implicated in a range of diseases, including mitochondrial disorders and neurodegenerative conditions. Investigating the role of ADCK1 in CoQ biosynthesis is critical for advancing our understanding of these diseases and developing potential therapeutic strategies to target mitochondrial dysfunction.
Antibody Name:
ADCK1 Antibody (PACO15319)
Antibody SKU:
PACO15319
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human ADCK1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15319(ADCK1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO15319(ADCK1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
