The ADAT2 Polyclonal Antibody (PACO07606) is a valuable tool for researchers studying the ADAT2 protein, involved in RNA editing and modification processes. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is validated for Western blot analysis. By binding specifically to ADAT2, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in RNA biology and related fields.ADAT2 is a crucial component of the ADAT complex, which catalyzes the deamination of adenosine to inosine in highly structured RNA molecules.
This modification plays a key role in diversifying the genetic code and regulating gene expression. Understanding the function and regulation of ADAT2 is essential for unraveling its impact on RNA processing and its potential implications in disease mechanisms.Overall, the ADAT2 Polyclonal Antibody (PACO07606) provides researchers with a reliable tool for investigating the role of ADAT2 in RNA editing processes and exploring its potential as a therapeutic target in various pathologies involving RNA dysregulation.
adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae);ADAT2;DEADC1;DKFZp686L1118;FLJ44213;TAD2;dJ20N2;dJ20N2.1 ;
UniProt Protein Function:
ADAT2: Probably participates in deamination of adenosine-34 to inosine in many tRNAs. Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; EC 3.5.4.-Chromosomal Location of Human Ortholog: 6q24.2Molecular Function: tRNA-specific adenosine deaminase activity; zinc ion bindingBiological Process: tRNA wobble adenosine to inosine editing
