The ADARB1 Polyclonal Antibody (CAB16748) is a valuable tool for researchers studying ADARB1, a key enzyme involved in RNA editing processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ADARB1 in human samples, making it ideal for use in Western blot applications. By binding to the ADARB1 protein, this antibody enables the detection and analysis of ADARB1 expression in various cell types, offering insights into its role in RNA editing and related cellular processes.ADARB1, also known as adenosine deaminase RNA-specific B1, is crucial for the editing of RNA molecules, impacting gene expression and protein function.
Dysregulation of ADARB1 has been linked to various diseases, including neurological disorders and cancer, making it a promising target for therapeutic interventions. Research on ADARB1 using this polyclonal antibody can provide valuable insights into its function and potential implications in disease pathology, paving the way for the development of novel treatment strategies.
Product Name:
ADARB1 Rabbit Polyclonal Antibody
SKU:
CAB16748
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ADARB1 (NP_001103.1).
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Purification Method:
Affinity purification
Gene ID:
104
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADARB1 Rabbit pAb (CAB16748) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
