The ADAR1 Monoclonal Antibody (CAB11466) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed and validated in rabbits, exhibits high specificity and sensitivity in detecting ADAR1 protein in various experimental settings, including Western blot and immunohistochemistry applications.ADAR1 plays a crucial role in RNA editing, impacting gene expression, protein function, and cellular processes. Dysregulation of ADAR1 has been linked to various diseases, including cancer, autoimmune disorders, and neurological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
ADAR1 Monoclonal Antibody
SKU:
CAB11466
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0602
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
103
RRID
AB_2861571
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ADAR1 Rabbit mAb (CAB11466) at 1：1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
