The ADAR1 Rabbit Monoclonal Antibody is a vital tool for researchers studying adenosine deaminase acting on RNA (ADAR1), an essential enzyme involved in RNA editing processes. This antibody, developed and validated in rabbits, exhibits high specificity and sensitivity in detecting ADAR1 protein in various experimental settings, including Western blot and immunohistochemistry applications.ADAR1 plays a crucial role in RNA editing, impacting gene expression, protein function, and cellular processes. Dysregulation of ADAR1 has been linked to various diseases, including cancer, autoimmune disorders, and neurological conditions.
By targeting ADAR1, researchers can gain insight into the mechanisms underlying these diseases and develop potential therapeutic strategies.With its superior performance and reliability, the ADAR1 Rabbit Monoclonal Antibody is an invaluable tool for researchers in molecular biology, genetics, and biomedical sciences. Its ability to specifically detect ADAR1 protein levels in diverse sample types makes it an indispensable asset for studying RNA editing mechanisms and their implications in human health and disease.
Product Name:
ADAR1 Rabbit Monoclonal Antibody
SKU:
CAB11466
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human ADAR1 (P55265).
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
103
Clone Number:
ARC0602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADAR1 Rabbit mAb (CAB11466) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
