The ADAMTS16 Polyclonal Antibody (PACO3572) is a valuable tool for researchers studying ADAMTS16, a member of the ADAMTS family of metalloproteases involved in extracellular matrix remodeling. This antibody, produced in rabbits, specifically targets ADAMTS16 in human samples and has been validated for use in Western blot applications. By binding to ADAMTS16, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in biology, specifically in the fields of extracellular matrix biology and tissue remodeling.
ADAMTS16 plays a crucial role in various physiological processes, including development, wound healing, and tissue repair. Dysregulation of ADAMTS16 has been linked to conditions such as arthritis, cancer, and cardiovascular disease, making it a promising target for therapeutic interventions. By understanding the function and regulation of ADAMTS16, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop novel treatment strategies.
Antibody Name:
ADAMTS16 Antibody
Antibody SKU:
PACO03572
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human ADAMTS-16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ADAMTS16; KIAA2029; A disintegrin and metalloproteinase with thrombospondin motifs 16; ADAM-TS 16; ADAM-TS16; ADAMTS-16
UniProt Protein Function:
ADAMTS16: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Protease; Motility/polarity/chemotaxis; EC 3.4.24.-; Secreted, signal peptideChromosomal Location of Human Ortholog: 5p15Cellular Component: proteinaceous extracellular matrixMolecular Function: zinc ion binding; metalloendopeptidase activityBiological Process: ureteric bud branching; proteolysis
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member. [provided by RefSeq, Jul 2008]
A disintegrin and metalloproteinase with thrombospondin motifs 16 preproprotein
NCBI Synonym Full Names:
ADAM metallopeptidase with thrombospondin type 1 motif, 16
NCBI Official Symbol:
ADAMTS16Â Â
NCBI Official Synonym Symbols:
ADAMTS16s Â
NCBI Protein Information:
A disintegrin and metalloproteinase with thrombospondin motifs 16; ADAM-TS 16; ADAM-TS16; ADAMTS-16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16
UniProt Protein Name:
A disintegrin and metalloproteinase with thrombospondin motifs 16
UniProt Synonym Protein Names:
Protein Family:
A disintegrin and metalloproteinase with thrombospondin motifs
