The ADAM7 Polyclonal Antibody (PAC015309) is a crucial tool for researchers studying ADAM7, a cell surface protein known for its role in cell adhesion and migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the ADAM7 protein, this antibody allows for the precise detection and analysis of ADAM7 in various cell types, making it an essential tool for studies in cell biology and cancer research.ADAM7 is a member of the ADAM (a disintegrin and metalloproteinase) family of proteins, which are involved in processes such as cell adhesion, migration, and proteolysis.
As such, ADAM7 has been implicated in various cellular functions and is known to play a role in cancer progression and metastasis. By gaining a better understanding of the function of ADAM7, researchers can uncover potential therapeutic targets for diseases such as cancer and inflammatory disorders.Overall, the ADAM7 Polyclonal Antibody (PAC015309) is a valuable tool for investigating the function of ADAM7 in various biological processes and diseases, paving the way for potential advancements in cancer treatment and other related fields.
Antibody Name:
ADAM7 Antibody (PACO15309)
Antibody SKU:
PACO15309
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human
Immunogen:
Fusion protein of human ADAM7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15309(ADAM7 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma.
Synonyms:
ADAM metallopeptidase domain 7
UniProt Protein Function:
May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein ().
