The ADAM33 Polyclonal Antibody (CAB8265) is a vital tool for researchers studying the ADAM33 protein, a member of the ADAM family of proteins involved in cell signaling processes. This high-quality antibody, produced from rabbit immunization, displays strong reactivity with human samples and has been rigorously validated for Western blot applications. By specifically binding to the ADAM33 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential asset for studies in molecular biology and disease mechanisms.
ADAM33 has been implicated in various pathological conditions, including asthma, COPD, and cancer, highlighting its significance in disease development and progression. By targeting ADAM33, researchers can uncover novel insights into the underlying molecular mechanisms of these diseases and potentially identify new therapeutic strategies. The ADAM33 Polyclonal Antibody is a key tool for unlocking the potential of ADAM33 research and advancing our understanding of its role in health and disease.
Product Name:
ADAM33 Rabbit Polyclonal Antibody
SKU:
CAB8265
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human ADAM33 (NP_001269376.1).
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
80332
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADAM33 antibody (CAB8265) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
