The ADAM32 Polyclonal Antibody (CAB14977) is a valuable tool for researchers studying ADAM32, a cell surface protein involved in various developmental processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ADAM32 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile option for studies in developmental biology and related fields.
ADAM32, a member of the ADAM (a disintegrin and metalloproteinase) family, plays a crucial role in processes such as cell adhesion, migration, and signaling. Its involvement in developmental pathways makes it a key target for research into conditions like cancer, neurodegenerative diseases, and developmental disorders. By understanding the function and regulation of ADAM32, researchers can gain valuable insights into these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
ADAM32 Rabbit Polyclonal Antibody
SKU:
CAB14977
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 703-787 of human ADAM32 (NP_659441.3).
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
203102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADAM32 Rabbit pAb (CAB14977) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
