In a similar vein, the ADAM28 Polyclonal Antibody (CAB9512) is a versatile tool for researchers studying ADAM28, a protein belonging to the ADAM (a disintegrin and metalloproteinase) family known for its role in cell adhesion and proteolysis. Raised in rabbits, this antibody exhibits strong reactivity with human samples, making it suitable for Western blot applications.ADAM28 is implicated in various physiological processes, including cell migration, proliferation, and differentiation. Its dysregulation has been linked to diseases such as cancer, cardiovascular disorders, and inflammatory conditions.
By targeting ADAM28 with this specific polyclonal antibody, researchers can detect and analyze the protein in different cell types, advancing studies in oncology, cardiovascular research, and inflammation biology.With its high specificity and sensitivity, the ADAM28 Polyclonal Antibody provides valuable insights into the function and regulation of ADAM28 in diverse biological contexts. Its use in research may lead to a better understanding of disease mechanisms and potentially identify new therapeutic targets for intervention.
Product Name:
ADAM28 Rabbit Polyclonal Antibody
SKU:
CAB9512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 199-440 of human ADAM28 (NP_055080.2).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
87kDa
Observed MW:
87kDa
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADAM28 antibody (CAB9512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
