The ADAM23 Polyclonal Antibody (CAB14263) is a valuable tool for researchers studying the ADAM23 protein, a member of the ADAM (A Disintegrin And Metalloproteinase) family involved in various cellular processes such as cell adhesion, migration, and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the ADAM23 protein, allowing for detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.
ADAM23 is known to play a crucial role in cell signaling pathways and has been implicated in tumor progression and metastasis, making it a potential target for cancer therapy. Its involvement in cell adhesion and migration also suggests a role in neurological disorders and developmental processes. Understanding the function and regulation of ADAM23 could provide valuable insights into these disease mechanisms and potentially lead to the development of targeted therapies.
Product Name:
ADAM23 Rabbit Polyclonal Antibody
SKU:
CAB14263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human ADAM23 (NP_003803.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
92kDa
Observed MW:
92kDa
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers.
Purification Method:
Affinity purification
Gene ID:
8745
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADAM23 Rabbit pAb (CAB14263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
