ADAM22 Rabbit Polyclonal Antibody (CAB10030)
- SKU:
- CAB10030
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ADAM22 Rabbit Polyclonal Antibody |
SKU: | CAB10030 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 of human ADAM22 (NP_004185.1). |
Sequence: | SKRQ LRRY PRNV EEET KYIE LMIV NDHL MFKK HRLS VVHT NTYA KSVV NMAD LIYK DQLK TRIV LVAM ETWA TDNK FAIS ENPL ITLR EFMK YRRD FIKE KSDA VHLF SGSQ FESS RSGA AYIG GICS LLKG GGVN EFGK TDLM AVTL AQSL AHNI GIIS DKRK LASG ECKC EDTW SG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | MDC2; DEE61; EIEE61; ADAM 22; ADAM22 |
Positive Sample: | SH-SY5Y,Mouse brain,Mouse kidney,Mouse heart,Rat kidney,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Membrane, Single-pass type I membrane protein, axon. |
Calculated MW: | 100kDa |
Observed MW: | 100kDa |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 53616 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |