UniProt Protein Function: | ADAM21: May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients.Protein type: EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Membrane protein, integralChromosomal Location of Human Ortholog: 14q24.1Cellular Component: plasma membraneMolecular Function: metallopeptidase activityBiological Process: binding of sperm to zona pellucida; single fertilization |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene expression is testis-specific. [provided by RefSeq, May 2011] |
UniProt Code: | Q9UKJ8 |
NCBI GenInfo Identifier: | 296434388 |
NCBI Gene ID: | 8747 |
NCBI Accession: | Q9UKJ8.2 |
UniProt Secondary Accession: | Q9UKJ8,O43507, Q2VPC6, Q32MR0 |
UniProt Related Accession: | Q9UKJ8 |
Molecular Weight: | 80,834 Da |
NCBI Full Name: | Disintegrin and metalloproteinase domain-containing protein 21 |
NCBI Synonym Full Names: | ADAM metallopeptidase domain 21 |
NCBI Official Symbol: | ADAM21Â Â |
NCBI Official Synonym Symbols: | ADAM31; ADAM 21Â Â |
NCBI Protein Information: | disintegrin and metalloproteinase domain-containing protein 21 |
UniProt Protein Name: | Disintegrin and metalloproteinase domain-containing protein 21 |
UniProt Synonym Protein Names: | |
Protein Family: | Disintegrin and metalloproteinase domain-containing protein |
UniProt Gene Name: | ADAM21Â Â |
UniProt Entry Name: | ADA21_HUMAN |