The ADAM2 Polyclonal Antibody (CAB10188) is a valuable tool for researchers studying ADAM2, a key protein involved in fertilization and cell adhesion processes. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the ADAM2 protein, this antibody allows for the detection and analysis of ADAM2 in various cell types, making it an ideal choice for studies in reproductive biology and developmental biology.
ADAM2, also known as fertilin alpha, plays a crucial role in sperm-egg interactions and the fusion of gametes during fertilization. Its involvement in these essential processes makes it a potential target for research on infertility, contraception, and reproductive disorders. By studying the function and regulation of ADAM2, researchers can gain valuable insights into mechanisms of fertility and potential therapeutic interventions for reproductive challenges.
Product Name:
ADAM2 Rabbit Polyclonal Antibody
SKU:
CAB10188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 476-686 of human ADAM2 (Q99965).
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
2515
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADAM2 antibody (CAB10188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
