ADAM19 Rabbit Polyclonal Antibody (CAB10260)
- SKU:
- CAB10260
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ADAM19 Rabbit Polyclonal Antibody |
SKU: | CAB10260 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_150377.1). |
Sequence: | REDL NSMK YVEL YLVA DYLE FQKN RRDQ DATK HKLI EIAN YVDK FYRS LNIR IALV GLEV WTHG NMCE VSEN PYST LWSF LSWR RKLL AQKY HDNA QLIT GMSF HGTT IGLA PLMA MCSV YQSG GVNM DHSE NAIG VAAT MAHE MGHN FGMT HDSA DCCS ASAA DGGC IMAA ATGH PFPK VFNG CNRR ELDR YLQS GGGM CLSN MPDT RMLY GGRR CGNG YLED GEEC DCGE EEEC NNPC CNAS NCTL RPGA ECAH GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | MLTNB; FKSG34; MADDAM; ADAM19 |
Positive Sample: | HT-1080,SW480,NIH/3T3,Mouse heart,Mouse lung,Mouse liver,Mouse kidney,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 105kDa |
Observed MW: | 72kDa |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.
Purification Method: | Affinity purification |
Gene ID: | 8728 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |