ADAM15 Rabbit Monoclonal Antibody (CAB6813)
- SKU:
- CAB6813
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | ADAM15 Rabbit Monoclonal Antibody |
SKU: | CAB6813 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ADAM15 (Q13444). |
Sequence: | RHIR RRRD VVTE TKTV ELVI VADH SEAQ KYRD FQHL LNRT LEVA LLLD TFFR PLNV RVAL VGLE AWTQ RDLV EISP NPAV TLEN FLHW RRAH LLPR LPHD S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | MDC15; ADAM15 |
Positive Sample: | HCT 116 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasmic vesicle, Endomembrane system, acrosome, adherens junction, cilium, flagellum, secretory vesicle. |
Calculated MW: | 55kDa/88kDa/89kDa/90kDa/93kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 8751 |
Clone Number: | ARC1419 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |