ADAM15 Rabbit Polyclonal Antibody (CAB7756)
- SKU:
- CAB7756
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
Product Name: | ADAM15 Rabbit Polyclonal Antibody |
SKU: | CAB7756 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-700 of human ADAM15 (NP_003806.3). |
Sequence: | QPAA PLCL QTAN TRGN AFGS CGRN PSGS YVSC TPRD AICG QLQC QTGR TQPL LGSI RDLL WETI DVNG TELN CSWV HLDL GSDV AQPL LTLP GTAC GPGL VCID HRCQ RVDL LGAQ ECRS KCHG HGVC DSNR HCYC EEGW APPD CTTQ LKAT SSLT TGLL L |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MDC15; ADAM15 |
Positive Sample: | Mouse heart,Mouse kidney,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasmic vesicle, Endomembrane system, Single-pass type I membrane protein, acrosome, adherens junction, cilium, flagellum, secretory vesicle. |
Calculated MW: | 93kDa |
Observed MW: | 93kDa |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 8751 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |