Adenosine Deaminase (ADA) Rabbit Monoclonal Antibody (CAB5151)
- SKU:
- CAB5151
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Adenosine Deaminase (ADA) Rabbit Monoclonal Antibody |
SKU: | CAB5151 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Adenosine Deaminase (ADA) (NP_000013.2). |
Sequence: | NRLR QENM HFEI CPWS SYLT GAWK PDTE HAVI RLKN DQAN YSLN TDDP LIFK STLD TDYQ MTKR DMGF TEEE FKRL NINA AKSS FLPE DEKR ELLD LLYK A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ADA1; Adenosine Deaminase (ADA) |
Positive Sample: | Jurkat,Mouse stomach,Rat thymus,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle lumen, Extracellular side, Peripheral membrane protein. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine in the purine catabolic pathway. Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined immunodeficiency disease (SCID) which is the result of a deficiency in the ADA enzyme. In ADA-deficient individuals there is a marked depletion of T, B, and NK lymphocytes, and consequently, a lack of both humoral and cellular immunity. Conversely, elevated levels of this enzyme are associated with congenital hemolytic anemia.
Purification Method: | Affinity purification |
Gene ID: | 100 |
Clone Number: | ARC1152 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |