ACVRL1 Rabbit Polyclonal Antibody (CAB1791)
- SKU:
- CAB1791
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | ACVRL1 Rabbit Polyclonal Antibody |
SKU: | CAB1791 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human ACVRL1 (NP_001070869.1). |
Sequence: | RDEQ SWFR ETEI YNTV LLRH DNIL GFIA SDMT SRNS STQL WLIT HYHE HGSL YDFL QRQT LEPH LALR LAVS AACG LAHL HVEI FGTQ GKPA IAHR DFKS RNVL VKSN LQCC IADL GLAV MHSQ GSDY LDIG NNPR VGTK RYMA PEVL DEQI RTDC FESY KWTD IWAF GLVL WEIA RRTI VNGI VEDY RPPF YDVV PNDP SFED MKKV VCVD QQTP TIPN RLAA DPVL SGLA QMMR ECWY PNPS ARLT ALRI KKTL QKIS NSPE KPKV IQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; ACVRL1 |
Positive Sample: | SH-SY5Y,HL-60,MCF7,Jurkat,Mouse lung,Mouse heart,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 65kDa |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Purification Method: | Affinity purification |
Gene ID: | 94 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |