ACVR1B Rabbit Polyclonal Antibody (CAB5453)
- SKU:
- CAB5453
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ACVR1B Rabbit Polyclonal Antibody |
SKU: | CAB5453 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-126 of human ACVR1B (NP_004293.1). |
Sequence: | SGPR GVQA LLCA CTSC LQAN YTCE TDGA CMVS IFNL DGME HHVR TCIP KVEL VPAG KPFY CLSS EDLR NTHC CYTD YCNR IDLR VPSG HLKE PEHP SMWG PVE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ALK4; SKR2; ACTRIB; ACVRLK4; ACVR1B |
Positive Sample: | SW480, Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 57kDa |
Observed MW: | 49kDa |
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 91 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |