The ACTR3 Polyclonal Antibody (CAB1064) is a valuable tool for researchers studying ACTR3, a key component of the Arp2/3 complex involved in actin polymerization and cell motility. This antibody, produced in rabbits, is highly specific for detecting ACTR3 in human samples and has been validated for use in Western blot applications. By binding to ACTR3, this antibody allows for the visualization and analysis of ACTR3 expression in various cell types, making it an essential reagent for investigations in cell biology and cancer research.ACTR3, also known as actin-related protein 3, plays a crucial role in regulating the dynamics of the actin cytoskeleton, which is essential for various cellular processes such as cell migration, division, and shape maintenance.
Dysregulation of ACTR3 has been implicated in cancer metastasis and other pathological conditions involving aberrant cell motility. Therefore, a thorough understanding of ACTR3 function is vital for developing targeted therapies to intervene in these disease processes.Invest in the ACTR3 Polyclonal Antibody (CAB1064) for precise and reliable detection of ACTR3 in your research studies, paving the way for novel insights into the roles of this protein in health and disease.
Product Name:
Arp3 Rabbit Polyclonal Antibody
SKU:
CAB1064
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human Arp3 (NP_005712.1).
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10096
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Arp3 antibody (CAB1064) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
