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ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)

SKU:
CPAB0641
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1D10AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)

The ACTN1 Polyclonal Antibody (CPAB0641) is a valuable tool for researchers studying ACTN1, a key protein involved in cell structure and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ACTN1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in cell biology and cancer research.ACTN1, also known as alpha-actinin-1, plays a crucial role in maintaining cell shape, adhesion, and movement by connecting the cytoskeleton to the cell membrane.

Dysregulation of ACTN1 has been implicated in various diseases, including cancer, muscular dystrophy, and neurological disorders. Understanding the function and regulation of ACTN1 is essential for developing targeted therapies and interventions for these conditions.Overall, the ACTN1 Polyclonal Antibody (CPAB0641) provides researchers with a reliable tool for studying the role of ACTN1 in cellular processes and disease pathogenesis, ultimately advancing our understanding of molecular mechanisms and potential therapeutic strategies.

Product Name:ACTN1 Antibody
Product Sku:CPAB0641
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ACTN1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACTN1 protein 1-249 amino acids purified from Ecoli.
Clone:PAT1D10AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:ACTN1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Synonyms:ACTN1, Actinin, Alpha 1, Alpha-Actinin Cytoskeletal Isoform, F-Actin Cross-Linking Protein, Non-Muscle Alpha-Actinin-1, BDPLT15, Actinin 1 Smooth Muscle, Alpha-Actinin-1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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