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Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody (CAB21727)

SKU:
CAB21727
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$155 - $431
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody
SKU:CAB21727
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Activator protein 2 (AP-2/TFAP2A) (NP_003211.1).
Sequence:RQSQ ESGL LHTH RGLP HQLS GLDP RRDY RRHE DLLH GPHA LSSG LGDL SIHS LPHA IEEV PHVE DPGI NIPD QTVI KKGP VSLS KSNS NAVS AIPI NKDN L
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:AP-2; BOFS; AP2TF; TFAP2; AP-2alpha; Activator protein 2 (AP-2/TFAP2A)
Positive Sample:HeLa,C6
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:48kDa
Observed MW:50kDa

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:7020
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Activator protein 2 (AP-2/TFAP2A) antibody (CAB21727) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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