The Actin Rabbit Polyclonal Antibody (CABC006) is a valuable tool for researchers studying actin, a key protein involved in cell structure and movement. This antibody, generated in rabbits, shows high reactivity with actin in human samples and is validated for use in Western blot applications. By binding specifically to actin, this antibody allows for the detection and analysis of actin expression in various cell types.Actin is essential for numerous cellular processes, including cell division, muscle contraction, and cell migration. Dysregulation of actin dynamics has been implicated in various diseases, such as cancer and neurological disorders.
By using the Actin Rabbit Polyclonal Antibody, researchers can gain insights into the role of actin in these pathological conditions and develop targeted therapies.Overall, the Actin Rabbit Polyclonal Antibody (CABC006) is a valuable tool for investigating the functions of actin in both normal and diseased states. Its high reactivity, specificity, and validation make it an ideal choice for researchers in the fields of cell biology, cancer research, and neuroscience.
Product Name:
β-Actin Rabbit Polyclonal Antibody
SKU:
CABC006
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human β-Actin (NP_001092.1).
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome.
Purification Method:
Affinity purification
Gene ID:
60
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using β-Actin Rabbit pAb (AC006) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
