The ACTBL2 Polyclonal Antibody (PAC022810) is a valuable tool for research involving ACTBL2, an actin-binding protein essential for cell structure and movement. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ACTBL2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.ACTBL2, also known as beta-actin-like protein 2, plays a crucial role in regulating cell shape and movement through its interaction with actin filaments.
Its importance in maintaining cellular structure and function makes it a promising target for investigating processes such as cell migration, division, and signaling. Understanding the function of ACTBL2 is essential for unraveling the mechanisms underlying various diseases, including cancer and developmental disorders. By studying ACTBL2, researchers can gain valuable insights into cellular dynamics and potentially identify novel therapeutic targets for disease intervention.
Antibody Name:
ACTBL2 Antibody (PACO22810)
Antibody SKU:
PACO22810
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ACTBL2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HepG2, HuvEc, Jurkat and A549 cells, using ACTBL2 antibody.
Background:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells By similarity.
Synonyms:
Beta-actin-like protein 2; Kappa-actin; ACTBL2;
UniProt Protein Function:
ACTBL2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with PFN1 and PFDN1. Belongs to the actin family.Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 5q11.2Cellular Component: cytoplasm; cytoskeleton; extracellular spaceMolecular Function: ATP binding
