Actb Antibody (PACO32444)
- SKU:
- PACO32444
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Actb Antibody (PACO32444)
The ACTB Monoclonal Antibody is a powerful tool for researchers studying beta-actin, a key cytoskeletal protein involved in cell structure and movement. This antibody, produced in mice, has high specificity for human samples and is validated for use in various applications including Western blot, immunofluorescence, and flow cytometry. By targeting beta-actin, this antibody allows for precise detection and analysis of the protein in different cellular contexts, making it indispensable for studies in cell biology, cancer research, and drug development.
Beta-actin is essential for cell motility, intracellular transport, and maintaining cell shape, making it a crucial player in various cellular processes. Dysregulation of beta-actin has been implicated in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases, highlighting the importance of studying its function and regulation. By using the ACTB Monoclonal Antibody, researchers can gain insights into the role of beta-actin in health and disease, paving the way for potential therapeutic interventions targeting this protein.
| Antibody Name: | Actb Antibody (PACO32444) |
| Antibody SKU: | PACO32444 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse Actin, cytoplasmic 1 protein (11-375AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Actb antibody at 2µg/ml Lane 1: Mouse spleen tissue Lane 2: 293T whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa . |
| Background: | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Synonyms: | Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed], Actb |
| UniProt Protein Function: | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the actin family of proteins. Actins are highly conserved proteins that are among the most abundant proteins in eukaryotic cells and are involved in cell motility, structure, and integrity. Localization, stability, and translation of the transcribed mRNA are regulated through the binding of multiple factors to its 3' UTR sequence. Homozygous knockout mice for this gene exhibit embryonic lethality. Numerous pseudogenes of this gene have been identified in the mouse genome. [provided by RefSeq, Sep 2015] |
| UniProt Code: | P60710 |
| NCBI GenInfo Identifier: | 6671509 |
| NCBI Gene ID: | 11461 |
| NCBI Accession: | NP_031419.1 |
| UniProt Secondary Accession: | P60710,P02570, P70514, P99021, Q11211, Q3TI89, Q3TVP6 Q64316, Q6ZWM3 |
| UniProt Related Accession: | P60710 |
| Molecular Weight: | 41,737 Da |
| NCBI Full Name: | actin, cytoplasmic 1 |
| NCBI Synonym Full Names: | actin, beta |
| NCBI Official Symbol: | Actb  |
| NCBI Official Synonym Symbols: | Actx; beta-actin; E430023M04Rik  |
| NCBI Protein Information: | actin, cytoplasmic 1 |
| UniProt Protein Name: | Actin, cytoplasmic 1 |
| UniProt Synonym Protein Names: | Beta-actin |
| Protein Family: | Actin |
| UniProt Gene Name: | Actb  |
| UniProt Entry Name: |
Related Products
ACTB Antibody (PACO24738)
ACTB Antibody (PACO07078)
ACTB Antibody (PACO06089)
ACTB Antibody (PACO07578)
ACTB Antibody (PACO23090)
ACTB Antibody (PACO28698)
ACTB Antibody (PACO17455)
ACTB Antibody (PACO21341)
