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ACTA1 Monoclonal Antibody [PAT2F5AT] (CPAB0698)

SKU:
CPAB0698
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2F5AT
Applications:
WB
ELISA
€149
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Description

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ACTA1 Monoclonal Antibody [PAT2F5AT] (CPAB0698)

The ACTA1 Polyclonal Antibody (CPAB0698) is a valuable tool for researchers studying ACTA1, a protein involved in muscle contraction. This antibody, produced in rabbits, has high reactivity with human samples and is suitable for use in various applications, including Western blotting. By binding to the ACTA1 protein, this antibody allows for the detection and analysis of ACTA1 in different cell types, making it an ideal choice for research in muscle biology and related fields.

ACTA1 is a key component of skeletal muscle fibers, playing a crucial role in muscle contraction and function. Dysregulation of ACTA1 expression or function has been implicated in various muscle disorders and myopathies, making it a target of interest in muscle research. By investigating the role of ACTA1 using this antibody, researchers can gain valuable insights into muscle physiology and potentially identify new therapeutic targets for muscle-related diseases.

Product Name:ACTA1 Antibody
Product Sku:CPAB0698
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ACTA1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACTA1 amino acids 13-377 purified from Ecoli.
Clone:PAT2F5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:ACTA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Actin is one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans .Actin or ACTA is aprotein localized in the I band of the myofibrils in the muscle, Acting together with myosin.Actin takes part in the contraction and relaxation of muscle. Actin exists as a monomer in low salt concentrations, but filaments form rapidly as salt concentration rises, with the consequent hydrolysis of ATP.Each actin protomer binds one molecule of ATP and has one high affinity site for either calcium or magnesium ions, as well as several low affinity sites. It occurs in globular (G-actin) and fibrous (F-actin) forms. Actin is found in all eukaryotic cells (except for nematode sperm). Its other activitiessuch as cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape.
Synonyms:ACTA, Actin, actin, alpha 1, skeletal muscle, alpha skeletal muscle actin, alpha skeletal muscle, alpha-actin-1, ASMA, CFTD, CFTDM, MPFD, NEM1, NEM2, NEM3.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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