The ACSS2 Rabbit Monoclonal Antibody is a powerful tool for researchers studying the Acetyl-CoA synthetase 2 (ACSS2) protein, an enzyme involved in cellular metabolism and lipid biosynthesis. This antibody, developed using cutting-edge technology, offers highly specific and sensitive detection of ACSS2 in a variety of samples, particularly in cancer research.ACSS2 is known to play a key role in metabolic reprogramming of tumor cells, promoting their growth and survival. By targeting ACSS2 with this antibody, researchers can gain valuable insights into the mechanisms underlying cancer progression and potentially identify new therapeutic targets.
With its superior performance in immunohistochemistry and other applications, the ACSS2 Rabbit Monoclonal Antibody is a valuable asset for studies aiming to unravel the complex interplay between metabolism and cancer. Its high affinity and specificity ensure reliable results, making it an essential tool for advancing our understanding of cancer biology.
Product Name:
ACSS2 Rabbit Monoclonal Antibody
SKU:
CAB12334
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACSS2 (Q9NR19).
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55902
Clone Number:
ARC0690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACSS2 Rabbit mAb (CAB12334) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
