The ACSS1 Polyclonal Antibody (CAB15007) is a valuable tool for researchers studying ACSS1, an enzyme involved in the metabolism of acetate. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ACSS1 plays a crucial role in cellular metabolism, specifically in acetate utilization for lipid synthesis and energy production. Dysregulation of ACSS1 has been linked to various diseases, including cancer, metabolic disorders, and neurological conditions.
By targeting ACSS1 with this antibody, researchers can investigate the role of acetate metabolism in disease pathogenesis and potentially identify new therapeutic targets.With the ability to detect and analyze ACSS1 protein expression in different cell types, this antibody is ideal for studies in metabolic regulation, cancer biology, and drug development. By gaining a better understanding of ACSS1 function, researchers may uncover novel insights into disease mechanisms and pave the way for innovative treatment strategies.
Product Name:
ACSS1 Rabbit Polyclonal Antibody
SKU:
CAB15007
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-689 of human ACSS1 (NP_115890.2).
This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
84532
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACSS1 Rabbit pAb (CAB15007) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
